Lu Le, M.D., Ph.D.

Lu Le, M.D., Ph.D.

Dr. Lu Le, M.D., Ph.D., received his Ph.D. in Microbiology, Immunology and Molecular Genetics, and his M.D. from the Medical Scientist Training Program at the University of California, Los Angeles. He completed an Internship in Internal Medicine at UCLA/St. Mary Medical Center, residency training in Dermatology and a postdoctoral fellowship in Cancer Biology from University of Texas Southwestern Medical Center. He is board certified by the American Board of Dermatology. Dr. Le sees patients in the Dermatology clinic and at the UTSW Comprehensive Neurofibromatosis clinic.

As a principal investigator in cancer biology, his laboratory investigates how genetic and tumor microenvironmental events interplay to regulate carcinogenesis. His research group utilizes Neurofibromatosis Type 1 (NF1), a common tumor predisposition human genetic disorder, as a model to (1) identify the cells of origin of tumorigenesis and (2) elucidate the roles of tumor microenvironment in cancer development. His major research goals are to understand mechanisms that initiate Neurofibroma genesis and drive their malignant transformation as well as to develop novel therapeutic targets for Neurofibroma. Research in Dr. Le’s laboratory is supported by grants from the National Cancer Institute of the National Institutes of Health as well as grants from the U.S. Department of Defense and the Burroughs Wellcome Fund.

Outside the lab, Dr. Le enjoys biking with his children, reading and spending time with family and friends.